Indacaterol acetate
Based on 4 publication(s) in Google Scholar
Indacaterol acetate is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol acetate inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol acetate can also be used in cardiovascular disease research.
For research use only. We do not sell to patients.
- CAS No.: 1000160-96-2
- Formula: C26H32N2O5
- Molecular Weight:452.54
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Indacaterol acetate
MoreAll Adrenergic Receptor Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 1000160-96-2
-
Molecular Weight 452.54
-
Formula C26H32N2O5
-
SMILES
OC1=CC=C([C@@H](O)CNC2CC(C=C(CC)C(CC)=C3)=C3C2)C4=C1NC(C=C4)=O.CC(O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (4)
-
Journal Impact Factor
-
Most Recent
-
J Chromatogr A
2024 Feb 22:1717:464696. PMID: 38310699 -
Drug Test Anal
High-throughput liquid chromatography tandem mass spectrometry assay as initial testing procedure for analysis of total urinary fraction. [Abstract]2021 Feb;13(2):283-298. PMID: 32852861 -
J Neuroimmunol
Mechanism underlying β2-AR agonist-mediated phenotypic conversion of LPS-activated microglial cells. [Abstract]2019 Jul 15:332:37-48. PMID: 30933849 -
bioRxiv
2025 May 29:2025.05.28.656715. PMID: 40502188
Purity & Documentation
References
[1]. Lee SU, et al. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation. Mol Cells. 2014 Aug;37(8):585-91. [Content Brief]
[2]. Calzetta L, et al. Effects of the new ultra-long-acting β2-AR agonist indacaterol in chronic treatment alone or in combination with the β1-AR blocker metoprolol on cardiac remodelling. 2015. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)