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Cat. No.: HY-N11028

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Isophysalin G

Isophysalin G is a steroid that inhibits NO production induced by Lipopolysaccharides (HY-D1056) in macrophages with an IC₅₀ of 64.01 μM.

For research use only. We do not sell to patients.

CAS No.: 152221-21-1
Formula: C₂₈H₃₀O₁₀
Molecular Weight:526.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

Isophysalin G Chemical Structure

CAS No.: 152221-21-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Isophysalin G is a steroid that inhibits NO production induced by Lipopolysaccharides (HY-D1056) in macrophages with an IC₅₀ of 64.01 μM^[1].

IC₅₀ & Target

IC50: 64.01 μM (NO production)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	64.01 μM Compound: 3, isophysalin G	Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite formation Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite formation	[PMID: 18348534]

Chemical Information

CAS No. 152221-21-1
Molecular Weight 526.53
Formula C₂₈H₃₀O₁₀
SMILES

C[C@]12[C@]34[C@]5([H])[C@]6([C@@](C(O[C@]2([H])C6)=O)([H])CO[C@](C5=O)([C@@]7([H])[C@]([C@@]8(C(C=C7)=C[C@H](CC8=O)O)C)([H])CC[C@@]4(C(O1)=O)O)O3)C
Structure Classification
- Steroids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Qiu L, et al. Steroids and flavonoids from Physalis alkekengi var. franchetii and their inhibitory effects on nitric oxide production. J Nat Prod. 2008 Apr;71(4):642-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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