eIF2B activator-1
eIF2B activator-1 (Compound 7a) is a eIF2B activator with a pEC50 value of 7.3. eIF2B activator-1 exhibits significant hERG inhibitory activity, with a pIC50 value of 5.7. eIF2B activator-1 can be used in research related to Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS).
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- No. CAS: 3118633-46-5
- Fòrmula: C22H22Cl2N2O6
- Peso molecular:481.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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eIF2 7.3 (pEC50) |
Chemical Information
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No. CAS 3118633-46-5
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Peso molecular 481.33
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Fòrmula C22H22Cl2N2O6
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SMILES
O=C(COC1=CC=C(Cl)C=C1)N[C@@H](CO[C@]([C@@H](CO2)NC(COC3=CC=C(Cl)C=C3)=O)4[H])[C@]42[H]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
eIF2B activator-1 Related Classifications
HY-181406 Related Classifications
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- eIF2B activator-1
- 3118633-46-5
- Eukaryotic Initiation Factor (eIF)
- Potassium Channel
- protein synthesis
- human ether-a-go-go-related gene
- hERG potassium channel
- cardiac repolarization
- parkinson's
- amyotrophic lateral sclerosis
- huntington's
- SH-SY5Y human neuroblastoma cells
- eIF2B-mediated signaling
- eukaryotic initiation factor 2 beta
- Inhibitor
- inhibitor
- inhibit