eIF2B activator-1
eIF2B activator-1 (Compound 7a) is a eIF2B activator with a pEC50 value of 7.3. eIF2B activator-1 exhibits significant hERG inhibitory activity, with a pIC50 value of 5.7. eIF2B activator-1 can be used in research related to Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS).
For research use only. We do not sell to patients.
- CAS No.: 3118633-46-5
- Formula: C22H22Cl2N2O6
- Molecular Weight:481.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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eIF2 7.3 (pEC50) |
Chemical Information
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CAS No. 3118633-46-5
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Molecular Weight 481.33
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Formula C22H22Cl2N2O6
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SMILES
O=C(COC1=CC=C(Cl)C=C1)N[C@@H](CO[C@]([C@@H](CO2)NC(COC3=CC=C(Cl)C=C3)=O)4[H])[C@]42[H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
eIF2B activator-1 Related Classifications
HY-181406 Related Classifications
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- eIF2B activator-1
- 3118633-46-5
- Eukaryotic Initiation Factor (eIF)
- Potassium Channel
- protein synthesis
- human ether-a-go-go-related gene
- hERG potassium channel
- cardiac repolarization
- parkinson's
- amyotrophic lateral sclerosis
- huntington's
- SH-SY5Y human neuroblastoma cells
- eIF2B-mediated signaling
- eukaryotic initiation factor 2 beta
- Inhibitor
- inhibitor
- inhibit