AGN 210676
AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.
For research use only. We do not sell to patients.
- CAS No.: 910562-15-1
- Formula: C23H29NO5S
- Molecular Weight:431.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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EP2 5 nM (EC50) |
hEP3 153 nM (EC50) |
hDP receptor 7749 nM (EC50) |
AGN 210676 (Compound 23) also is a less potent agonist for recombinant human prostaglandin receptors hEP3A and hDP with EC50s of 153 nM and 7749 nM, respectively. AGN 210676 is useful for the treatment of glaucoma, ocular hypertension, inflammatory bowel disease, and the other diseases or conditions disclosed herein[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 910562-15-1
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Molecular Weight 431.55
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Formula C23H29NO5S
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SMILES
O=C(C1=CC=C(COC[C@@H](CC2)N(C3=CC=C([C@@H](O)CCCCC)C=C3)C2=O)S1)O
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Synonyms
Simenepag
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)