Daurisoline-d11
Daurisoline-d11 is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer.
For research use only. We do not sell to patients.
- Formula: C37H31D11N2O6
- Molecular Weight:621.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 70553-76-3
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Molecular Weight 621.81
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Formula C37H31D11N2O6
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SMILES
OC1=C(C2=C(CCN([C@@H]2CC3=C(C([2H])=C(C(OC4=C(C([2H])=C(C([2H])=C4[2H])C[C@H]5N(CCC6=C5C([2H])=C(C(OC)=C6[2H])OC)C)[2H])=C3[2H])O)[2H])C)C([2H])=C1OC)[2H]
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Synonyms
(R,R)-Daurisoline-d11
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Liu Q, et al. Effect of daurisoline on HERG channel electrophysiological function and protein expression. J Nat Prod. 2012 Sep 28;75(9):1539-45. [Content Brief]
[2]. Wu MY, et al. Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity. Oncotarget. 2017 Sep 8;8(44):77673-77684. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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