Dieckol
Based on 1 Customer Validation
Dieckol, is a naturally occurring phlorotannin found in some brown algal species. Dieckol has anti-bacterial, anti-cancer, anti-oxidant, anti-aging, anti-diabetic, neuroprotective actions.
For research use only. We do not sell to patients.
- Purity: 99.20%
- CAS No.: 88095-77-6
- Formula: C36H22O18
- Molecular Weight:742.55
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Anti-Infection Compound Library
HY-L002
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Natural Product Library
HY-L021
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
HY-L034
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Anti-diabetic Compound Library
HY-L040
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Antibacterial Compound Library
HY-L049
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Medicine Food Homology Compound Library
HY-L055
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Phenols Library
HY-L057
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Traditional Chinese Medicine Active Compound Library
HY-L065
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Neuroprotective Compound Library
HY-L070
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Microbial Metabolite Library
HY-L084
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Anti-Cancer Natural Product Library
HY-L107
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Human Metabolite Library
HY-L123
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Marine-Sourced Natural Product Library
HY-L143
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Natural Product Library Plus
HY-L021P
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Natural Product and Natural Product-Like Compound Library
HY-L021M
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Bioactive Compound Library
HY-L001
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Tibetan Medicine Compound Library
HY-L191
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PBCRBS Traditional Chinese Medicine Compound Library
HY-L193
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High-Throughput Bioactive Compound Library
HY-L205
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High-Throughput Natural Product Library
HY-L206
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Ancient Chinese Classical Formulas Traditional Chinese Medicine Active Compound Library
HY-L209
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Mass Spectrometry Human Metabolite Library
HY-L215
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Cosmetic Ingredient Compound Library
HY-L221
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Antitussive and Antiasthmatic Traditional Chinese Medicine Active Compound Library
HY-L223
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Diarrhea-Related Traditional Chinese Medicine Active Compound Library
HY-L224
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Mongolian Medicine Compound Library
HY-L238
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Natural Product Diversity Scaffold Library
HY-L245
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Mass Spectrometry Natural Product Library
HY-L262
Biological Activity
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Cell Line
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Type | Value | Description | References |
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| Vero | CC50 |
>200 μM
Compound: 8
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Cytotoxicity against african green monkey Vero cells assessed as cell death by MTT assay
Cytotoxicity against african green monkey Vero cells assessed as cell death by MTT assay
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[PMID: 23647823] |
| Vero | IC50 |
68.1 μM
Compound: 8
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Inhibition of SARS coronavirus 3C-like protease cis-cleavage activity transfected in african green monkey Vero cells using SAVLQSGFRK as substrate after 5 hrs by luciferase reporter gene assay
Inhibition of SARS coronavirus 3C-like protease cis-cleavage activity transfected in african green monkey Vero cells using SAVLQSGFRK as substrate after 5 hrs by luciferase reporter gene assay
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[PMID: 23647823] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 88095-77-6
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Appearance Solid
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Molecular Weight 742.55
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Formula C36H22O18
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Color Off-white to light brown
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SMILES
OC1=CC(OC2=C(C=C(C3=C2OC4=C(O)C=C(OC5=C(C=C(C=C5O)OC6=C(C=C(C7=C6OC8=C(C=C(C=C8O)O)O7)O)O)O)C=C4O3)O)O)=CC(O)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (67.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (3.37 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.3467 mL | 6.7336 mL | 13.4671 mL | 33.6678 mL |
| 5 mM | 0.2693 mL | 1.3467 mL | 2.6934 mL | 6.7336 mL | |
| 10 mM | 0.1347 mL | 0.6734 mL | 1.3467 mL | 3.3668 mL | |
| 15 mM | 0.0898 mL | 0.4489 mL | 0.8978 mL | 2.2445 mL | |
| 20 mM | 0.0673 mL | 0.3367 mL | 0.6734 mL | 1.6834 mL | |
| 25 mM | 0.0539 mL | 0.2693 mL | 0.5387 mL | 1.3467 mL | |
| 30 mM | 0.0449 mL | 0.2245 mL | 0.4489 mL | 1.1223 mL | |
| 40 mM | 0.0337 mL | 0.1683 mL | 0.3367 mL | 0.8417 mL | |
| 50 mM | 0.0269 mL | 0.1347 mL | 0.2693 mL | 0.6734 mL | |
| 60 mM | 0.0224 mL | 0.1122 mL | 0.2245 mL | 0.5611 mL |
Dieckol Related Classifications
HY-147059 Related Classifications
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