Izuralimab
Based on 1 Customer Validation
Izuralimab is a bispecific IgG1 antibody targeting inducible T-cell costimulator (ICOS/CD278) and PD-1.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 2329669-80-7
- Molecular Weight:126.283 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3
Human
PDCD1 & ICOS
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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half-IGG1-kappa/(scFv-kappa-heavy)-h-CH2-CH3
ELISA, FACS, Functional assay
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Immobilized PD-1 Protein, Human (143a.a, HEK293, His, HY-P7396) can bind Izuralimab. The EC50 for this effect is 8.806 ng/mL. -
Immobilized ICOS Protein, Human (HEK293, Fc, HY-P72618) can bind Izuralimab. The EC50 for this effect is 62.25 ng/mL.
Chemical Information
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CAS No. 2329669-80-7
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Appearance Liquid
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Molecular Weight 126.283 kDa
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Color Colorless to light yellow
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SMILES
[Izuralimab]
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)