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Cat. No.: HY-P3228

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JKC 302

JKC 302 is an ET-A receptor antagonist. JKC 302 partly blocks ET-1-induced contraction in asthmatic rat trachea ring.

For research use only. We do not sell to patients.

CAS No.: 153982-38-8
Formula: C₃₀H₄₂N₆O₆
Molecular Weight:582.69

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

JKC 302 Chemical Structure

CAS No.: 153982-38-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

JKC 302 is an ET-A receptor antagonist. JKC 302 partly blocks ET-1-induced contraction in asthmatic rat trachea ring^[1]^[2].

All Endothelin Receptor Isoforms :

ET_A
ET_B

Chemical Information

CAS No. 153982-38-8
Molecular Weight 582.69
Formula C₃₀H₄₂N₆O₆
Sequence

Cyclo({d-Ser}-Pro-{d-Val}-Leu-{d-Trp})
Sequence Shortening

Cyclo({d-Ser}-W-{d-Val}-P-{d-Trp})
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Basilico N, et al. The lipid moiety of haemozoin (Malaria Pigment) and P. falciparum parasitised red blood cells bind synthetic and native endothelin-1. J Biomed Biotechnol. 2010;2010:854927. [Content Brief]

[2]. Tiequn HUANG, et al. Role of endothelin and nitric oxide in the pathogenesis of asthma. Chinese Journal of Pathophysiology ; (12): 435-437, 2001.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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