ITSA-1 (Standard)
ITSA-1 (Standard) is the analytical standard of ITSA-1 (HY-100508). This product is intended for research and analytical applications. ITSA-1 is an activator of histone deacetylase (HDAC), and counteract trichostatin A (TSA)-induced cell cycle arrest, histone acetylation, and transcriptional activation.
For research use only. We do not sell to patients.
- CAS No.: 200626-61-5
- Formula: C13H7Cl2N3O
- Molecular Weight:292.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 200626-61-5
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Molecular Weight 292.12
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Formula C13H7Cl2N3O
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SMILES
O=C(N1N=NC2=CC=CC=C21)C3=CC=C(Cl)C=C3Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Koeller KM et al. Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histoneand tubulin acetylation. Chem Biol. 2003 May;10(5):397-410. [Content Brief]
[2]. Behera J, et al. Hydrogen Sulfide Promotes Bone Homeostasis by Balancing Inflammatory Cytokine Signaling in CBS-Deficient Mice through an Epigenetic Mechanism. Sci Rep. 2018 Oct 15;8(1):15226. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)