IUB0271
IUB0271 (acyl-GIP) is a fatty acylated and long-acting glucose-dependent insulinotropic polypeptide (GIP). IUB0271 increases cFos neuronal activity in hypothalamic feeding centers and decreases body weight, food intake and glycemia in DIO mouse models, and these effects depend on CNS-GIPR signaling. IUB0271 can be used for type 2 diabetes mellitus (T2DM) and obesity research.
For research use only. We do not sell to patients.
- Formula: C264H403N65O77S
- Molecular Weight:5751.48
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
Molecular Weight 5751.48
-
Formula C264H403N65O77S
-
Synonyms
acyl-GIP
-
Sequence
Tyr-{Aib}-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-Lys(γGlu-γGlu-γGlu-C16)
-
Sequence Shortening
Y-{Aib}-EGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ-Lys(γGlu-γGlu-γGlu-C16)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)