2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK
  4. JAK-2/3-IN-2

JAK-2/3-IN-2 (Compound 3h) is a JAK2 and JAK3 inhibitor with IC50s of 23.85 nM and 18.9 nM, respectively.

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JAK-2/3-IN-2 Chemical Structure

JAK-2/3-IN-2 Chemical Structure

CAS No. : 2170398-48-6

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JAK-2/3-IN-2 Related Antibodies

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Description

JAK-2/3-IN-2 (Compound 3h) is a JAK2 and JAK3 inhibitor with IC50s of 23.85 nM and 18.9 nM, respectively[1].

IC50 & Target[1]

JAK3

18.9 nM (IC50)

JAK2

23.85 nM (IC50)

Molecular Weight

358.88

Formula

C19H19ClN2OS
CAS No.
SMILES

O=C1N(C2=CC=CC=C2Cl)N(CC)C(C)=C1SC3=CC=C(C)C=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JAK-2/3-IN-2 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JAK-2/3-IN-22170398-48-6JAKJanus kinaseInhibitorinhibitorinhibit

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