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Jedi2 

Cat. No.: HY-131018
Handling Instructions

Jedi2 is a Piezo1 channel activator, but no specific Piezo2 activators. Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770  μM.

For research use only. We do not sell to patients.

Jedi2 Chemical Structure

Jedi2 Chemical Structure

CAS No. : 651005-90-2

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Description

Jedi2 is a Piezo1 channel activator, but no specific Piezo2 activators. Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770  μM[1].

In Vitro

Jedi2 evokes Piezo1-mediated Ca2+ influx. Jedi2 (200 μM) specifically elicits dose-dependent responses in mPiezo1-transfected cells, but not in mPiezo2- or vector-transfected cells [1].
Jedi2 (1 mM) causes an increase in Ca2+ in mCherry-positive HEK293T cells transfected with the mPiezo1-mCherry construct, which also responded to Yoda1 (30 μM) [1].

Molecular Weight

208.23

Formula

C₁₀H₈O₃S

CAS No.

651005-90-2

SMILES

O=C(C1=C(C)OC(C2=CC=CS2)=C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Jedi2Jedi 2Jedi-2OthersInhibitorinhibitorinhibit

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