JMS-038
JMS-038 is a PTP4A3 inhibitor with an IC50 of 0.018 μM against human PTP4A3. JMS-038 can be used in ovarian cancer-related research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 86126-60-5
- Fòrmula: C12H8N2O2S
- Peso molecular:244.27
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
hPTP4A3 0.018 μM (IC50) |
In Vitro
JMS-038 (Compound 21) is a PTP4A3 inhibitor. PTP4A3 is an oncogenic dual-specificity protein tyrosine phosphatase whose core functions are to drive tumor proliferation, migration and metastasis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 86126-60-5
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Peso molecular 244.27
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Fòrmula C12H8N2O2S
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SMILES
O=C1NC(C2=C(N1)SC(C3=CC=CC=C3)=C2)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Salamoun JM, et al. Photooxygenation of an amino-thienopyridone yields a more potent PTP4A3 inhibitor. Org Biomol Chem. 2016;14(27):6398-6402. [Content Brief]
[2]. McQueeney KE, et al. Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor. Oncotarget. 2017;9(9):8223-8240. Published 2017 Dec 30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JMS-038 Related Classifications
HY-183953 Related Classifications
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