JMS-038
JMS-038 is a PTP4A3 inhibitor with an IC50 of 0.018 μM against human PTP4A3. JMS-038 can be used in ovarian cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 86126-60-5
- Formula: C12H8N2O2S
- Molecular Weight:244.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hPTP4A3 0.018 μM (IC50) |
JMS-038 (Compound 21) is a PTP4A3 inhibitor. PTP4A3 is an oncogenic dual-specificity protein tyrosine phosphatase whose core functions are to drive tumor proliferation, migration and metastasis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 86126-60-5
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Molecular Weight 244.27
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Formula C12H8N2O2S
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SMILES
O=C1NC(C2=C(N1)SC(C3=CC=CC=C3)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Salamoun JM, et al. Photooxygenation of an amino-thienopyridone yields a more potent PTP4A3 inhibitor. Org Biomol Chem. 2016;14(27):6398-6402. [Content Brief]
[2]. McQueeney KE, et al. Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor. Oncotarget. 2017;9(9):8223-8240. Published 2017 Dec 30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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