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Cat. No.: HY-N10985

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Xanthone V1a

Xanthone V1a, a derivative of Xanthone (HY-N0126), is an antioxidant that can be found in the roots of Cudrania tricuspidata and twig extracts of Maclura fruticosa. Xanthone V1a exerts cytotoxic effects against colon, hepatocellular, and gastric carcinoma cells. Xanthone V1a exhibits scavenging activitys against DPPH and ABTS. Xanthone V1a can be used for the research of colon carcinoma, hepatocellular carcinoma, and gastric carcinoma.

For research use only. We do not sell to patients.

CAS No.: 103450-96-0
Formula: C₂₃H₂₄O₆
Molecular Weight:396.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Xanthone V1a Chemical Structure

CAS No.: 103450-96-0

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Xanthone V1a(72 h) exhibits significant cytotoxicity against HCT-116, SMMC-7721, and SGC-7901 cell lines with IC₅₀ values of 0.3, 6.2, and 3.4 μg/mL, respectively, showing no cytotoxicity against BGC-823 cells^[1].
Xanthone V1a (30 min) shows significant anti-oxidant activity against the DPPH radical an IC50 of 10.43 μM^[2].
Xanthone V1a (200 μg/mL, 5 min) inhibits ABTS with an inhibition of 93.69%^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 103450-96-0
Molecular Weight 396.43
Formula C₂₃H₂₄O₆
SMILES

C/C(C)=C\CC(C(O)=C12)=C(O)C(C/C=C(C)\C)=C2OC3=C(C=CC(O)=C3O)C1=O
Structure Classification
- Flavonoids
- Other Flavonoids
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zou YS, et al. Cytotoxic isoprenylated xanthones from Cudrania tricuspidata. Bioorg Med Chem. 2004 Apr 15;12(8):1947-53. [Content Brief]

[2]. Isaraporn Polbuppha, et al. Antioxidant, Cytotoxic and α-Glucosidase Inhibitory Activities of
Compounds isolated from the Twig Extracts of Maclura fruticosa. Natural Product Communications Vol. 12 (7) 2017.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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