14-Hydroxytetradecanoic acid
Based on 1 Customer Validation
14-Hydroxytetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : ≥97.0%
- CAS 番号: 17278-74-9
- 分子式: C14H28O3
- 分子量:244.38
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保管条件:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
PROTACs contain two different ligands connected by a linker; one is a ligand for an E122 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 17278-74-9
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性状 Solid
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分子量 244.38
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分子式 C14H28O3
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SMILES
O=C(O)CCCCCCCCCCCCCO
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
体外:
DMSO : ≥ 100 mg/mL (409.20 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (237 KB)
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SDS (393 KB)
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- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0920 mL | 20.4599 mL | 40.9199 mL | 102.2997 mL |
| 5 mM | 0.8184 mL | 4.0920 mL | 8.1840 mL | 20.4599 mL | |
| 10 mM | 0.4092 mL | 2.0460 mL | 4.0920 mL | 10.2300 mL | |
| 15 mM | 0.2728 mL | 1.3640 mL | 2.7280 mL | 6.8200 mL | |
| 20 mM | 0.2046 mL | 1.0230 mL | 2.0460 mL | 5.1150 mL | |
| 25 mM | 0.1637 mL | 0.8184 mL | 1.6368 mL | 4.0920 mL | |
| 30 mM | 0.1364 mL | 0.6820 mL | 1.3640 mL | 3.4100 mL | |
| 40 mM | 0.1023 mL | 0.5115 mL | 1.0230 mL | 2.5575 mL | |
| 50 mM | 0.0818 mL | 0.4092 mL | 0.8184 mL | 2.0460 mL | |
| 60 mM | 0.0682 mL | 0.3410 mL | 0.6820 mL | 1.7050 mL | |
| 80 mM | 0.0511 mL | 0.2557 mL | 0.5115 mL | 1.2787 mL | |
| 100 mM | 0.0409 mL | 0.2046 mL | 0.4092 mL | 1.0230 mL |