4-Hydroxyacetophenone oxime
Based on 1 Customer Validation
4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.96%
- CAS 番号: 34523-34-7
- 分子式: C8H9NO2
- 分子量:151.16
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保管条件:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
生物活性
化学情報
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CAS 番号 34523-34-7
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性状 Solid
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分子量 151.16
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分子式 C8H9NO2
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Color White to off-white
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SMILES
C/C(C1=CC=C(O)C=C1)=N\O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (661.55 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (769 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22(2): p. 383-90. [Content Brief]
[2]. Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8(6):553-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.6155 mL | 33.0775 mL | 66.1551 mL | 165.3877 mL |
| 5 mM | 1.3231 mL | 6.6155 mL | 13.2310 mL | 33.0775 mL | |
| 10 mM | 0.6616 mL | 3.3078 mL | 6.6155 mL | 16.5388 mL | |
| 15 mM | 0.4410 mL | 2.2052 mL | 4.4103 mL | 11.0258 mL | |
| 20 mM | 0.3308 mL | 1.6539 mL | 3.3078 mL | 8.2694 mL | |
| 25 mM | 0.2646 mL | 1.3231 mL | 2.6462 mL | 6.6155 mL | |
| 30 mM | 0.2205 mL | 1.1026 mL | 2.2052 mL | 5.5129 mL | |
| 40 mM | 0.1654 mL | 0.8269 mL | 1.6539 mL | 4.1347 mL | |
| 50 mM | 0.1323 mL | 0.6616 mL | 1.3231 mL | 3.3078 mL | |
| 60 mM | 0.1103 mL | 0.5513 mL | 1.1026 mL | 2.7565 mL | |
| 80 mM | 0.0827 mL | 0.4135 mL | 0.8269 mL | 2.0673 mL | |
| 100 mM | 0.0662 mL | 0.3308 mL | 0.6616 mL | 1.6539 mL |