Rilmazafone hydrochloride
Based on 1 Customer Validation
Rilmazafone hydrochloride (450191S) is a benzodiazepine (omega) ligand.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.57%
- CAS 番号: 85815-37-8
- 分子式: C21H21Cl3N6O3
- 分子量:511.79
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
製品説明
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 85815-37-8
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性状 Solid
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分子量 511.79
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分子式 C21H21Cl3N6O3
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Color White to off-white
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SMILES
NCC(NCC1=NC(C(N(C)C)=O)=NN1C2=C(C=C(Cl)C=C2)C(C3=C(C=CC=C3)Cl)=O)=O.Cl
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別名
450191S
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 250 mg/mL (488.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Yasui M, et al. [Pharmacological profiles of benzodiazepinergic hypnotics and correlations with receptor subtypes]. Nihon Shinkei Seishin Yakurigaku Zasshi. 2005 Jun;25(3):143-51. [Content Brief]
[2]. Matsubara T, et al. Effect of change of hepatic drug-metabolizing activity on plasma concentrations of major metabolites of the new sleep inducer 450191-S, a 1H-1,2,4-triazolyl benzophenone derivative. Jpn J Pharmacol. 1987 Aug;44(4):429-36. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9539 mL | 9.7696 mL | 19.5393 mL | 48.8482 mL |
| 5 mM | 0.3908 mL | 1.9539 mL | 3.9079 mL | 9.7696 mL | |
| 10 mM | 0.1954 mL | 0.9770 mL | 1.9539 mL | 4.8848 mL | |
| 15 mM | 0.1303 mL | 0.6513 mL | 1.3026 mL | 3.2565 mL | |
| 20 mM | 0.0977 mL | 0.4885 mL | 0.9770 mL | 2.4424 mL | |
| 25 mM | 0.0782 mL | 0.3908 mL | 0.7816 mL | 1.9539 mL | |
| 30 mM | 0.0651 mL | 0.3257 mL | 0.6513 mL | 1.6283 mL | |
| 40 mM | 0.0488 mL | 0.2442 mL | 0.4885 mL | 1.2212 mL | |
| 50 mM | 0.0391 mL | 0.1954 mL | 0.3908 mL | 0.9770 mL | |
| 60 mM | 0.0326 mL | 0.1628 mL | 0.3257 mL | 0.8141 mL | |
| 80 mM | 0.0244 mL | 0.1221 mL | 0.2442 mL | 0.6106 mL | |
| 100 mM | 0.0195 mL | 0.0977 mL | 0.1954 mL | 0.4885 mL |