Calcitetrol
Based on 1 Customer Validation
Calcitetrol (1α, 24, 25-Trihydroxy VD3), a Vitamin D3 (HY-15398) metabolite, is the hormonally active form of vitamin D. Calcitetrol participates in regulation of Treg cells. Calcitetrol can be used for the research of Toxoplasma gondii infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.94%
- CAS 番号: 72203-93-1
- 分子式: C27H44O4
- 分子量:432.64
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保管条件:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Calcitetrol undergoes further metabolism by recombinant rat kidney calcidiol 24-hydroxylase (P450cc24) into 24-oxo-1,25-dihydroxyvitamin D3, which converts to 24-oxo-1,23,25-trihydroxyvitamin D3[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 72203-93-1
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性状 Solid
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分子量 432.64
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分子式 C27H44O4
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Color White to off-white
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SMILES
O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCC(O)C(C)(O)C)C)([H])[C@]3(C)CCC\2
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別名
1α, 24, 25-Trihydroxy VD3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (231.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Ma J, et al. Metabolomic signature of mouse cerebral cortex following Toxoplasma gondii infection. Parasit Vectors. 2019;12(1):373. Published 2019 Jul 29. [Content Brief]
[2]. Akiyoshi-Shibata M, et al. Further oxidation of hydroxycalcidiol by calcidiol 24-hydroxylase. A study with the mature enzyme expressed in Escherichia coli. Eur J Biochem. 1994;224(2):335-343. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3114 mL | 11.5570 mL | 23.1139 mL | 57.7848 mL |
| 5 mM | 0.4623 mL | 2.3114 mL | 4.6228 mL | 11.5570 mL | |
| 10 mM | 0.2311 mL | 1.1557 mL | 2.3114 mL | 5.7785 mL | |
| 15 mM | 0.1541 mL | 0.7705 mL | 1.5409 mL | 3.8523 mL | |
| 20 mM | 0.1156 mL | 0.5778 mL | 1.1557 mL | 2.8892 mL | |
| 25 mM | 0.0925 mL | 0.4623 mL | 0.9246 mL | 2.3114 mL | |
| 30 mM | 0.0770 mL | 0.3852 mL | 0.7705 mL | 1.9262 mL | |
| 40 mM | 0.0578 mL | 0.2889 mL | 0.5778 mL | 1.4446 mL | |
| 50 mM | 0.0462 mL | 0.2311 mL | 0.4623 mL | 1.1557 mL | |
| 60 mM | 0.0385 mL | 0.1926 mL | 0.3852 mL | 0.9631 mL | |
| 80 mM | 0.0289 mL | 0.1445 mL | 0.2889 mL | 0.7223 mL | |
| 100 mM | 0.0231 mL | 0.1156 mL | 0.2311 mL | 0.5778 mL |
Calcitetrol 関連分類
HY-15157 関連分類
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