D-Fructose-6-phosphate
D-Fructose 6-phosphate is an endogenous metabolite. D-Fructose 6-phosphate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate can be used to study Lewy body dementia.
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- CAS 番号: 643-13-0
- 分子式: C6H13O9P
- 分子量:260.14
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
D-Fructose-6-phosphate (3.2 mM; room temperature) can detect transaldolase TAL activity[3].
D-Fructose-6-phosphate (10 mM; incubation at 37°C for 60 min) can complete the detection of glucosamine-6-phosphate synthase activity[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 643-13-0
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性状 Solid
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分子量 260.14
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分子式 C6H13O9P
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Color White to off-white
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SMILES
OCC([C@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)=O
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
純度とドキュメンテーション
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データシート (267 KB)
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- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Lee JH, et al. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry. 2001 Jul 3;40(26):7799-805. [Content Brief]
[2]. Hardie DG, et al. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):251-62. [Content Brief]
[3]. Puskas F, et al. Stimulation of the pentose phosphate pathway and glutathione levels by dehydroascorbate, the oxidized form of vitamin C. FASEB J. 2000 Jul;14(10):1352-61. [Content Brief]
[4]. Hiramatsu M, et al. Suppression by thyroid hormones of glucosamine-6-phosphate synthetase activity in rat sublingual glands. Arch Oral Biol. 1984;29(10):849-51. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
D-Fructose-6-phosphate 関連分類
HY-113407 関連分類
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