Pasiniazid
Based on 1 Customer Validation
Pasiniazid is a chemical complex formed by Isoniazid (HY-B0329) and Para-aminosalicylic acid in a 1:1 molar ratio. Pasiniazid is an antibacterial agent. Pasiniazid is rapidly decomposed into isoniazid and para-aminosalicylic acid in the gastrointestinal tract. Isoniazid exerts a bactericidal effect, while para-aminosalicylic acid delays the acetylation process of isoniazid. Pasiniazid has antibacterial activity against Mycobacterium tuberculosis. Pasiniazid can be used in tuberculosis research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 2066-89-9
- 分子式: C13H14N4O4
- 分子量:290.27
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
生物活性
Pasiniazid (0.125-256 μg/mL) shows that 85 out of 109 INH-resistant Mycobacterium tuberculosis isolates are susceptible to it[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2066-89-9
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性状 Solid
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分子量 290.27
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分子式 C13H14N4O4
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Color Light yellow to khaki
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SMILES
O=C(C1=CC=NC=C1)NN.O=C(O)C2=CC=C(N)C=C2O
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別名
Paraniazide; Pasiniazide; Isonicotinic acid hydrazide p-aminosalicylate
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
DMSO : 100 mg/mL (344.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4451 mL | 17.2253 mL | 34.4507 mL | 86.1267 mL |
| 5 mM | 0.6890 mL | 3.4451 mL | 6.8901 mL | 17.2253 mL | |
| 10 mM | 0.3445 mL | 1.7225 mL | 3.4451 mL | 8.6127 mL | |
| 15 mM | 0.2297 mL | 1.1484 mL | 2.2967 mL | 5.7418 mL | |
| 20 mM | 0.1723 mL | 0.8613 mL | 1.7225 mL | 4.3063 mL | |
| 25 mM | 0.1378 mL | 0.6890 mL | 1.3780 mL | 3.4451 mL | |
| 30 mM | 0.1148 mL | 0.5742 mL | 1.1484 mL | 2.8709 mL | |
| 40 mM | 0.0861 mL | 0.4306 mL | 0.8613 mL | 2.1532 mL | |
| 50 mM | 0.0689 mL | 0.3445 mL | 0.6890 mL | 1.7225 mL | |
| 60 mM | 0.0574 mL | 0.2871 mL | 0.5742 mL | 1.4354 mL | |
| 80 mM | 0.0431 mL | 0.2153 mL | 0.4306 mL | 1.0766 mL | |
| 100 mM | 0.0345 mL | 0.1723 mL | 0.3445 mL | 0.8613 mL |