Progabide
Based on 1 Customer Validation
Progabide is a gamma-aminobutyric acid receptor (GABA) agonist.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.50%
- CAS 番号: 62666-20-0
- 分子式: C17H16ClFN2O2
- 分子量:334.77
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
GABA receptor[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 62666-20-0
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性状 Solid
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分子量 334.77
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分子式 C17H16ClFN2O2
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Color Light yellow to yellow
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SMILES
O=C(N)CCC/N=C(C1=CC=C(Cl)C=C1)\C2=CC(F)=CC=C2O
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別名
SL 76002
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 250 mg/mL (746.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
Male Wistar rats weighing 170 to 240 g are caged in groups of three under diurnal lighting conditions with free access to food and water. The rats are accustomed to handling (housing 1 per cage for 30 min, injecting with saline, 1 mL/100 g body weight) in the period of 7 days before the beginning of the experiment. Progabide is injected as a suspension in saline containing 0.1% Tween 80. Control rats are treated IP with the corresponding vehicle (1 mL/100 g body weight). Ether stress is performed and 15 min after the beginning of the stressful procedure the animals are sacrificed[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
純度とドキュメンテーション
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データシート (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9871 mL | 14.9356 mL | 29.8713 mL | 74.6781 mL |
| 5 mM | 0.5974 mL | 2.9871 mL | 5.9743 mL | 14.9356 mL | |
| 10 mM | 0.2987 mL | 1.4936 mL | 2.9871 mL | 7.4678 mL | |
| 15 mM | 0.1991 mL | 0.9957 mL | 1.9914 mL | 4.9785 mL | |
| 20 mM | 0.1494 mL | 0.7468 mL | 1.4936 mL | 3.7339 mL | |
| 25 mM | 0.1195 mL | 0.5974 mL | 1.1949 mL | 2.9871 mL | |
| 30 mM | 0.0996 mL | 0.4979 mL | 0.9957 mL | 2.4893 mL | |
| 40 mM | 0.0747 mL | 0.3734 mL | 0.7468 mL | 1.8670 mL | |
| 50 mM | 0.0597 mL | 0.2987 mL | 0.5974 mL | 1.4936 mL | |
| 60 mM | 0.0498 mL | 0.2489 mL | 0.4979 mL | 1.2446 mL | |
| 80 mM | 0.0373 mL | 0.1867 mL | 0.3734 mL | 0.9335 mL | |
| 100 mM | 0.0299 mL | 0.1494 mL | 0.2987 mL | 0.7468 mL |
Progabide 関連分類
HY-A0173 関連分類
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