A-1293102
A-1293102 is a potent and selective BCL-XL inhibitor that kills BCL-XL-dependent tumor cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1565759-96-7
- 分子式: C42H40F3N7O7S5
- 分子量:972.13
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MOLT-4 | EC50 |
0.08 μM
Compound: 4; A-1293102
|
Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay
Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay
|
[PMID: 34141086] |
| RS4-11 | EC50 |
>5 μM
Compound: 4; A-1293102
|
Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay
Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay
|
[PMID: 34141086] |
化学情報
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CAS 番号 1565759-96-7
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分子量 972.13
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分子式 C42H40F3N7O7S5
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SMILES
O=C(C1=C2C(CCN(C3=NC(C(NS(=O)(C4=CC(S(C(F)(F)F)(=O)=O)=C(C=C4)N[C@@H](CSC5=CC=CC=C5)CCN6CCOCC6)=O)=O)=CS3)C2)=CC=C1)NC7=NC8=CC=CC=C8S7
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)