AB-22
AB-22, a vinyl sulfate compound, is an orally active antifungal agent. AB-22 inhibits hyphal growth and biofilm initiation by inhibiting the gene expression of ALS3, HWP1, and ECE1 in Candida albicans SC5314 cells. AB-22 can be used for the research of infrction, such as systemic candidiasis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1463913-43-0
- 分子式: C22H30ClN7O3
- 分子量:475.97
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
AB-22 (4 μg/mL; 30-120 mins) delays germ tube formation of SC5314 cells[1].
AB-22 (0.25-3 h) inhibits hyphal growth and biofilm initiation by inhibiting the gene expression of ALS3, HWP1, and ECE1 in SC5314 cells[1].
AB-22 (0.5-4 μg/mL; 24 hours) inhibits hyphal growth of SC5314 cells[1].
AB-22 (1-4 μg/mL; 24 hours) inhibits biofilm formation of SC5314 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:ICR mice infected with C. albicans ATCC90028 cells (male, 7-weeks-old)[1]
-
Dosage:20 and 30 mg/kg, twice a day for 5 days or 300 mg/kg for a single dose
-
Administration:Orally administration
-
Result:Prolonged survival time and increased survival rate.
化学情報
-
CAS 番号 1463913-43-0
-
分子量 475.97
-
分子式 C22H30ClN7O3
-
SMILES
O=C(NN(CCO)C1=CC(C(C)C)=C(C(C)=NN2C)C2=N1)NC3=CC(OCCC)=NC(Cl)=C3
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AB-22 関連分類
HY-178732 関連分類
Powered by Bioz