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製品番号: HY-W725454

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Acetaminosalol

Acetaminosalol, a merged ester NSAID–APAP hybrid, is a metabolite of Benorylate (HY-107795) and a prodrug of Acetaminophen (HY-66005) and Aalicylic acid (HY-B0167). Acetaminosalol can be used for the research of acute rheumatism.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 118-57-0
分子式: C₁₅H₁₃NO₄
分子量:271.27

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Acetaminosalol 構造式

CAS 番号: 118-57-0

容量

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	Inhibition	102.732 % Compound: ACETAMINOSALOL	Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM	[PMID: 23571415]
CHO	Inhibition	103.085 % Compound: ACETAMINOSALOL	Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM	[PMID: 23571415]

体外実験

Acetaminosalol (Compound 47) is a chemically stable prodrug that resists gastric juice hydrolysis, undergoes enzymatic hydrolysis in human plasma and rat liver homogenate to release active Aalicylic acid (HY-B0167) and Acetaminophen (HY-66005)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 118-57-0
分子量 271.27
分子式 C₁₅H₁₃NO₄
SMILES

O=C(OC1=CC=C(C=C1)NC(=O)C)C=2C=CC=CC2O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Kouznetsov VV, et al. Exploring acetaminophen prodrugs and hybrids: a review. RSC Adv. 2024;14(14):9691-9715. Published 2024 Mar 22. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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