ACG548B
Based on 1 Customer Validation
ACG548B (compound 24) is a potent inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50s of 1.78 and 0.496 μM, respectively. ACG548B has higher AChE affinity and selectivity over BChE and ChoK (choline kinase). ACG548B can be uesd for the study of myasthenia gravis and neuromuscular blockade.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.72%
- CAS 番号: 795316-16-4
- 分子式: C38H34Br2Cl2N4
- 分子量:777.42
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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AChE 1.78 μM (IC50) |
BChE 0.496 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | IC50 |
1.9 μM
Compound: 19
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Antiproliferative activity was determined using HT-29 human colon cancer cell line
Antiproliferative activity was determined using HT-29 human colon cancer cell line
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[PMID: 15481981] |
化学情報
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CAS 番号 795316-16-4
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性状 Solid
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分子量 777.42
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分子式 C38H34Br2Cl2N4
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Color Yellow to brown
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SMILES
CN(C1=CC=[N+](CC2=CC(C3=CC=CC(C[N+]4=CC=C(N(C5=CC=C(Cl)C=C5)C)C=C4)=C3)=CC=C2)C=C1)C6=CC=C(Cl)C=C6.[Br-].[Br-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (64.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2863 mL | 6.4315 mL | 12.8631 mL | 32.1577 mL |
| 5 mM | 0.2573 mL | 1.2863 mL | 2.5726 mL | 6.4315 mL | |
| 10 mM | 0.1286 mL | 0.6432 mL | 1.2863 mL | 3.2158 mL | |
| 15 mM | 0.0858 mL | 0.4288 mL | 0.8575 mL | 2.1438 mL | |
| 20 mM | 0.0643 mL | 0.3216 mL | 0.6432 mL | 1.6079 mL | |
| 25 mM | 0.0515 mL | 0.2573 mL | 0.5145 mL | 1.2863 mL | |
| 30 mM | 0.0429 mL | 0.2144 mL | 0.4288 mL | 1.0719 mL | |
| 40 mM | 0.0322 mL | 0.1608 mL | 0.3216 mL | 0.8039 mL | |
| 50 mM | 0.0257 mL | 0.1286 mL | 0.2573 mL | 0.6432 mL | |
| 60 mM | 0.0214 mL | 0.1072 mL | 0.2144 mL | 0.5360 mL |
ACG548B 関連分類
HY-122140 関連分類
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