Acutumidine
Based on 1 Customer Validation
Acutumidine is a chlorinated alkaloid present in the cultured roots of Menispermum dauricum and Hypserpa nitida Miers. Acutumidine exhibits anti-HBV activity, with an IC50 value of 2.023 mM against hepatitis B virus surface antigen. Acutumidine can be used in studies related to hepatitis B.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.0%
- CAS 番号: 18145-26-1
- 分子式: C18H22ClNO6
- 分子量:383.82
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | CC50 |
>2.888 mM
Compound: 4
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Cytotoxicity against human Hep G2.2.15 cells
Cytotoxicity against human Hep G2.2.15 cells
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[PMID: 17723297] |
| HepG2 2.2.15 | IC50 |
>2.888 mM
Compound: 4
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Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of e antigen HBsAg secretion
Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of e antigen HBsAg secretion
|
[PMID: 17723297] |
| HepG2 2.2.15 | IC50 |
2.023 mM
Compound: 4
|
Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of surface antigen HBsAg secretion
Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of surface antigen HBsAg secretion
|
[PMID: 17723297] |
体外実験
Acutumidine (compound 4) inhibits HBsAg secretion in Hep G2.2.15 cells with an IC50 of 2.023 mM, has no activity against HBeAg at concentrations greater than 2.888 mM, and exhibits a selectivity index greater than 1.31[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 18145-26-1
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性状 Solid
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分子量 383.82
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分子式 C18H22ClNO6
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Color White to off-white
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SMILES
COC([C@@]12[C@](C3)(CCN2)[C@]4([C@@H](C(OC)=CC4=O)O)[C@H](C1)Cl)=C(OC)C3=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
純度とドキュメンテーション
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データシート (294 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Acutumidine 関連分類
HY-N15419 関連分類
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