Aderbasib (Standard)
Aderbasib (Standard) is the analytical standard of Aderbasib (HY-10293). This product is intended for research and analytical applications. Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17. Aderbasib exhibits robust antineoplastic activity and can be used for cancer research, including diffuse large B-cell non-Hodgkin lymphoma, HER2+ breast cancer, gliomas, et al.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 791828-58-5
- 分子式: C21H28N4O5
- 分子量:416.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
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HY-10293
AderbasibADAM10/17 Inhibitor -
HY-148905
p-Aminophenylmercuric acetateMatrix Metalloproteinases Activator -
HY-12169
MarimastatMMP Inhibitor -
HY-B2162
Chondroitin sulfateGlycosaminoglycan -
HY-13564
BatimastatMMP Inhibitor -
HY-19956
GI254023XADAM10/MMP9 Inhibitor -
HY-B2162D
Chondroitin sulfate (from chicken)Sulfated Linear Polysaccharide -
HY-N0532
MorronisidePyroptosis Inhibitor -
HY-B2162A
Chondroitin sulfate sodium (from shark cartilage)Glycosaminoglycan -
HY-B2162C
Chondroitin sulfate (from pig)Sulfated Linear Polysaccharide -
HY-118694
TAPI-0TACE/MMP Inhibitor -
HY-103068
Diethyl-pythiDCCP4H Inhibitor
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 791828-58-5
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分子量 416.47
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分子式 C21H28N4O5
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SMILES
O=C(N(CC1)CCN1C2=CC=CC=C2)[C@H]([C@H](C3)C(NO)=O)N(CC43CC4)C(OC)=O
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別名
INCB007839 (Standard); INCB7839 (Standard)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Lois Witters, et al. Synergistic inhibition with a dual epidermal growth factor receptor/HER-2/neu tyrosine kinase inhibitor and a disintegrin and metalloprotease inhibitor. Cancer Res. 2008 Sep 1;68(17):7083-9. [Content Brief]
[2]. Fei Yuan, et al. ADAM17 is an essential attachment factor for classical swine fever virus. PLoS Pathog. 2021 Mar 8;17(3):e1009393. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Aderbasib (Standard) 関連分類
HY-10293R 関連分類
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