ALLO-647
ALLO-647 is a human monoclonal antibody targeting CD52. ALLO-647 transiently and selectively depletes host lymphocytes to promote the proliferation of allogeneic CAR T-cell following infusion. ALLO-647 can be used for the research of B-cell lymphoma and follicular lymphoma.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Human
ALLO-647 is a human monoclonal antibody targeting CD52, a GPI-anchored low-molecular-weight glycoprotein that is highly expressed on almost all mature T and B cells but not on hematopoietic stem cells. Soluble CD52 is a natural inhibitor of the NF‑κB pathway, which mainly functions in myeloid cells and also exerts cross-regulation in T/B cells.[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
CD52
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
化学情報
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)