Anticancer agent 101
Anticancer agent 101 is a derivative of tetracaine. Anticancer agent 101 has anti-cancer activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2914922-80-6
- 分子式: C19H20F3N3O
- 分子量:363.38
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Anticancer agent 101 (compound 2m; 24 and 48 h) has antitumor activity with IC50 values of 20.5 μM and 62.9 μM against Colo-205 and HepG2 cells, respectively[1].
Anticancer agent 101 (25 µM and 50 µM; 24 h) down-regulates the expression level of apoptotic protein PI3K and FoXO3a, up-regulates the expression level of PTEN and FoXO1 in Colo-205 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Colo-205 and HepG2 cells
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Concentration:12.5, 25, 50, 100, 200, and 400 µM
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Incubation Time:24 and 48 hours
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Result:Inhibited cell growth in a dose-dependent manner.
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Cell Line:Colo-205 cell
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Concentration:25 µM and 50 µM
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Incubation Time:24 hours
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Result:Down-regulated the expression level of apoptotic protein PI3K and FoXO3a, up-regulated the expression level of PTEN and FoXO1 in Colo-205 cells
化学情報
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CAS 番号 2914922-80-6
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分子量 363.38
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分子式 C19H20F3N3O
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SMILES
O=C(N/N=C/C1=CC=CC=C1C(F)(F)F)C2=CC=C(NCCCC)C=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Anticancer agent 101 関連分類
HY-149215 関連分類
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