Anticancer agent 151
Anticancer agent 151 (compound 6C) is an anticancer agent. Anticancer agent 151 exhibits excellent in vitro cytotoxic activity against MCF-7 cells with an IC50 value of 6.3 μM.
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- CAS 番号: 1227476-97-2
- 分子式: C22H18Cl2N2O3
- 分子量:429.30
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
>10 μM
Compound: 6c
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Cytotoxicity against human K562 cells after 72 hrs by calcein-AM assay
Cytotoxicity against human K562 cells after 72 hrs by calcein-AM assay
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[PMID: 23981532] |
| MCF7 | IC50 |
7.9 μM
Compound: 6c
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Cytotoxicity against human MCF7 cells after 72 hrs by calcein-AM assay
Cytotoxicity against human MCF7 cells after 72 hrs by calcein-AM assay
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[PMID: 23981532] |
化学情報
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CAS 番号 1227476-97-2
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分子量 429.30
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分子式 C22H18Cl2N2O3
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SMILES
O=C(C1=C(C=CC(Cl)=C1)O)N[C@H](C(NC2=CC=C(C=C2)Cl)=O)CC3=CC=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Imramovský A, et al. Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines. Eur J Med Chem. 2013;68:253-259. [Content Brief]
[2]. Aleš Imramovský, et al. Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines. Eur J Med Chem. 2013. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Anticancer agent 151 関連分類
HY-155167 関連分類
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