Apoptosis inducer 8
Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2470024-51-0
- 分子式: C29H22ClN5O2
- 分子量:507.97
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Galectin アイソフォーム固有の製品をすべて表示
More
生物活性
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Galectin-1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.63 μM
Compound: 74
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Anticancer activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Anticancer activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
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[PMID: 34146913] |
| MCF7 | IC50 |
1.3 μM
Compound: 74
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Anticancer activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Anticancer activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
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[PMID: 34146913] |
| NCI-H460 | IC50 |
0.99 μM
Compound: 74
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Anticancer activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Anticancer activity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
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[PMID: 34146913] |
Apoptosis inducer 8 (Compound 7c) exhibits an excellent growth inhibition against A-549, NCI-H460, MCF-7 and MDA-MB-23 cells with IC50 values of 0.63 ± 0.21, 0.99 ± 0.01, 1.3 ± 0.18 and 0.94 ± 0.02 µM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2470024-51-0
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分子量 507.97
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分子式 C29H22ClN5O2
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SMILES
OC1=CC=CC(N2N=NC(COC3=CC=C(C4=NC5=CC(Cl)=CC=C5N4CC6=CC=CC=C6)C=C3)=C2)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Apoptosis inducer 8 関連分類
HY-147865 関連分類
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