AQ-13
AQ-13 (Compound 7) is a Chloroquine (HY-17589A) analogue with anti-breast cancer property. AQ-13 shows antiproliferative activities against MDA-MB231 and MCF7 with GI50 of 27.81 and 17.85 μM. AQ-13 shows low cytotoxicity against non-cancerous breast epithelial cells MCF10A (GI50 = 65.26 μM). AQ-13 can be used for the research of breast cancer.
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- CAS 番号: 32571-49-6
- 分子式: C16H22ClN3
- 分子量:291.82
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF-10A | GI50 |
65.26 μM
Compound: 7
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Antiproliferative activity against human MCF10A cells after 48 hrs by SRB assay
Antiproliferative activity against human MCF10A cells after 48 hrs by SRB assay
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[PMID: 20561720] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 32571-49-6
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分子量 291.82
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分子式 C16H22ClN3
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SMILES
ClC1=CC2=NC=CC(NCCCN(CC)CC)=C2C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AQ-13 関連分類
HY-178822 関連分類
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