BAA-009
BAA-009 is a selective and orally active PKMYT1 inhibitor with an IC50 of <50 nM. BAA-009 inhibits cancer cells proliferation and inhibits tumor growth in OVCAR3 xenograft mice. BAA-009 can be used for the research of cancer, such as ovarian cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C28H35N5O4S
- 分子量:537.67
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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PKMYT1 <50 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:human ovarian cancer OVCAR3 xenograft mice models[1]
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Dosage:40, 120 mg/kg
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Administration:p.o.; qd for 17 days
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Result:Inhibited tumor growth.
Showed stronger antitumor activity combined with Irinotecan (HY-16562) and ADC Mirvetuximab exatecan.
化学情報
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分子量 537.67
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分子式 C28H35N5O4S
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SMILES
CC(C)(C)C(OC1=CC=C(C)C(NC(C2=CN=C(NC3=NC(NC(C(C)(C)C)=O)=CC=C3C)S2)=O)=C1C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
BAA-009 関連分類
HY-182791 関連分類
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