BChE-IN-34
BChE-IN-34 is a potent and selective butyrylcholinesterase (BChE) inhibitor with an IIC50 of 25 nM. BChE-IN-34 shows excellent selectivity against BChE over acetylcholinesterase. BChE-IN-34 has neuroprotective and antioxidant effects.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2215768-12-8
- 分子式: C21H19N5O2S2
- 分子量:437.54
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
eqBCHE 25 nM (IC50) |
BChE-IN-34 (compound 35a) has moderate inhibition potency on β-Amyloid (1-42) (HY-P1363A) aggregation, and significant neuroprotective effect against SH-SY5Y cell injury induced by H2O2 and β-Amyloid (1-42)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 2215768-12-8
-
分子量 437.54
-
分子式 C21H19N5O2S2
-
SMILES
O=C(CSC1=NN=C(COC2=CC=CC3=C2C=CC=C3)N1CC=C)NC4=NC=CS4
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)