Brefonalol
Brefonalol (Brefanolol) is an orally active, non-selective β-adrenergic receptor blocker with vasodilatory properties. Brefonalol exhibits an optimal balance between β-blockade and vasodilatory effects at low doses: it reduces blood pressure and slows heart rate, while increasing stroke volume instead of decreasing it, causing no significant elevation in peripheral resistance and increasing reactive hyperemia; at high doses, the β-blockade effect dominates. Brefonalol can be used in the research of arterial hypertension.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 103880-26-8
- 分子式: C22H28N2O2
- 分子量:352.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Adrenergic Receptor アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
Brefonalol exhibits balanced β-receptor blocking and vasodilatory effects at a dose of 50 mg, while at a dose of 100 mg, it primarily exerts β-receptor blocking effects[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 103880-26-8
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分子量 352.47
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分子式 C22H28N2O2
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SMILES
O=C1NC2=C(C=C(C(O)CNC(C)(C)CCC3=CC=CC=C3)C=C2)CC1
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別名
Brefanolol
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)