Copper tripeptide-3
Based on 1 Customer Validation
Copper tripeptide-3 (AHK-Cu) is a bioactive peptide with promotion of hair growth effect. Copper tripeptide-3 increases dermal cell proliferation and viability while increasing the deposition of collagen to renew the extracellular matrix. Copper tripeptide-3 stimulates the elongation of human hair follicles and proliferation of dermal papilla cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.03%
- CAS 番号: 767286-83-9
- 分子式: C15H24CuN6O4
- 分子量:415.93
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
Copper tripeptide-3 (10-100 μM, 3 d) increases the growth and viability of dermal fibroblasts while stimulating the production of collagen in normal human dermal fibroblasts[2].
Copper tripeptide-3 (10 pM-10 nM, 24 h) significantly stimulates the proliferation of cultured dermal papilla cells[1].
Copper tripeptide-3 (10 nM, 72 h) reduces the number of apoptotic dermal papilla cells by 3.48%[1].
Copper tripeptide-3 (10 nM, 24 h) increases Bcl-2 expression and decreases Bax expression in dermal papilla cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Normal human dermal fibroblasts
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Concentration:10-100 μM
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Incubation Time:3 d
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Result:Stimulated the formation of collagen type I by 300% compared to the control.
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Cell Line:Normal human dermal fibroblasts
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Concentration:10 nM
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Incubation Time:72 h
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Result:Downregulated the levels of cleaved capase-3 and PARP cleavage fragments by 42.7% and 77.5%.
化学情報
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CAS 番号 767286-83-9
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性状 Solid
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分子量 415.93
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分子式 C15H24CuN6O4
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Color Light blue to blue
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別名
AHK-Cu
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配列
Ala-His-{Lys-Cu}
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シーケンスの短縮
AH-{Lys-Cu}
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
H2O : 25 mg/mL (60.11 mM; Need ultrasonic)
DMSO : 25 mg/mL (60.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 2.4043 mL | 12.0213 mL | 24.0425 mL | 60.1063 mL |
| 5 mM | 0.4809 mL | 2.4043 mL | 4.8085 mL | 12.0213 mL | |
| 10 mM | 0.2404 mL | 1.2021 mL | 2.4043 mL | 6.0106 mL | |
| 15 mM | 0.1603 mL | 0.8014 mL | 1.6028 mL | 4.0071 mL | |
| 20 mM | 0.1202 mL | 0.6011 mL | 1.2021 mL | 3.0053 mL | |
| 25 mM | 0.0962 mL | 0.4809 mL | 0.9617 mL | 2.4043 mL | |
| 30 mM | 0.0801 mL | 0.4007 mL | 0.8014 mL | 2.0035 mL | |
| 40 mM | 0.0601 mL | 0.3005 mL | 0.6011 mL | 1.5027 mL | |
| 50 mM | 0.0481 mL | 0.2404 mL | 0.4809 mL | 1.2021 mL | |
| 60 mM | 0.0401 mL | 0.2004 mL | 0.4007 mL | 1.0018 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Copper tripeptide-3 関連分類
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