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製品番号: HY-N2570

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Corytuberine

Corytuberine is an aporphine alkaloid found in Dicranostigma leptopodum. Corytuberine displays cytotoxicity against SMMC-7721 tumor cells.

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CAS 番号: 517-56-6
分子式: C₁₉H₂₁NO₄
分子量:327.37

保管条件:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Corytuberine 構造式

CAS 番号: 517-56-6

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価格（税別）

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Corytuberine is an aporphine alkaloid found in Dicranostigma leptopodum. Corytuberine displays cytotoxicity against SMMC-7721 tumor cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
B-cell	IC₅₀	21.3 μM Compound: 12	Inhibition of LPS-induced BALB/c mouse B cell proliferation Inhibition of LPS-induced BALB/c mouse B cell proliferation	[PMID: 17081761]
HeLa	IC₅₀	>200 μM Compound: 3	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 29103873]
HepG2	IC₅₀	>200 μM Compound: 3	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 29103873]
MGC-803	IC₅₀	>200 μM Compound: 3	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 29103873]
T-cell	IC₅₀	23.2 μM Compound: 12	Inhibition of ConA-induced BALB/c mouse T cell proliferation Inhibition of ConA-induced BALB/c mouse T cell proliferation	[PMID: 17081761]

化学情報

CAS 番号 517-56-6
性状 Solid
分子量 327.37
分子式 C₁₉H₂₁NO₄
SMILES

OC1=C2C3=C(C=C1OC)CCN(C)[C@@]3([H])CC4=CC=C(OC)C(O)=C24
Structure Classification
- Alkaloids
- Piperidine Alkaloids
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (271 KB)
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- Portuguese - PT (251 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Sun R, et al. Cytotoxicity of Aporphine, Protoberberine, and Protopine Alkaloids from Dicranostigma leptopodum (Maxim.) Fedde. Evid Based Complement Alternat Med. 2014;2014:580483. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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