CP320626
CP320626 is a potent inhibitor of human liver glycogen phosphorylase (IC50=205 nM). CP320626 reduces blood glucose in diabetic mice without changing plasma insulin levels. CP320626 can be used in the study of type 2 diabetes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 186430-23-9
- 分子式: C23H23ClFN3O3
- 分子量:443.90
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
1.7 μM
Compound: CP-320626
|
Inhibition of glucagon-induced glycogenolysis in Sprague-Dawley rat hepatocytes
Inhibition of glucagon-induced glycogenolysis in Sprague-Dawley rat hepatocytes
|
[PMID: 18434170] |
| Hepatocyte | IC50 |
1.7 μM
Compound: CP-320626
|
Inhibition of glucagon-induced glucose output in cultured rat primary hepatocytes
Inhibition of glucagon-induced glucose output in cultured rat primary hepatocytes
|
[PMID: 18952447] |
化学情報
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CAS 番号 186430-23-9
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分子量 443.90
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分子式 C23H23ClFN3O3
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SMILES
O=C(C(N1)=CC2=C1C=CC(Cl)=C2)N[C@@H](CC3=CC=C(F)C=C3)C(N4CCC(O)CC4)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)