Creatine-d3
Based on 2 publication(s) in Google Scholar
Creatine-d3 is the deuterium labeled Creatine (HY-W010388). Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.92%
- CAS 番号: 143827-19-4
- 分子式: C4H6D3N3O2
- 分子量:134.15
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
MedChemExpress(MCE)の使用を引用している文献 Creatine-d3
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 143827-19-4
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非標識Cas 57-00-1
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性状 Solid
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分子量 134.15
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分子式 C4H6D3N3O2
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Color White to off-white
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SMILES
OC(CN(C([2H])([2H])[2H])C(N)=N)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
2025 Jan;12(2):e2411015. PMID: 39569747 -
Phytomedicine
The hidden potential of solasonine: Targeting non-small cell lung cancer (NSCLC) metastasis through GATM and Smad2 pathways. [Abstract]2025 Apr:139:156455. PMID: 39922150
溶剤 & 溶解度
H2O : 16.67 mg/mL (124.26 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Nouioua S, et al. Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency. Neuromuscul Disord. 2013 Aug;23(8):670-4. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.4543 mL | 37.2717 mL | 74.5434 mL | 186.3586 mL |
| 5 mM | 1.4909 mL | 7.4543 mL | 14.9087 mL | 37.2717 mL | |
| 10 mM | 0.7454 mL | 3.7272 mL | 7.4543 mL | 18.6359 mL | |
| 15 mM | 0.4970 mL | 2.4848 mL | 4.9696 mL | 12.4239 mL | |
| 20 mM | 0.3727 mL | 1.8636 mL | 3.7272 mL | 9.3179 mL | |
| 25 mM | 0.2982 mL | 1.4909 mL | 2.9817 mL | 7.4543 mL | |
| 30 mM | 0.2485 mL | 1.2424 mL | 2.4848 mL | 6.2120 mL | |
| 40 mM | 0.1864 mL | 0.9318 mL | 1.8636 mL | 4.6590 mL | |
| 50 mM | 0.1491 mL | 0.7454 mL | 1.4909 mL | 3.7272 mL | |
| 60 mM | 0.1242 mL | 0.6212 mL | 1.2424 mL | 3.1060 mL | |
| 80 mM | 0.0932 mL | 0.4659 mL | 0.9318 mL | 2.3295 mL | |
| 100 mM | 0.0745 mL | 0.3727 mL | 0.7454 mL | 1.8636 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.