Cyclamic Acid-d11
Based on 1 Customer Validation
Cyclamic Acid-d11 is the deuterium labeled Cyclamic acid. Cyclamic acid (Cyclohexylsulfamic acid) is one of the most widely used artificial sweetenersin food and pharmaceuticals.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.90%
- CAS 番号: 1215770-73-2
- 分子式: C6H2D11NO3S
- 分子量:190.31
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
体外実験
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 1215770-73-2
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非標識Cas 100-88-9
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性状 Solid
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分子量 190.31
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分子式 C6H2D11NO3S
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Color White to off-white
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SMILES
O=S(NC1([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H])(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
H2O : 100 mg/mL (525.46 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Leban I, et, al. Structures of artificial sweeteners--cyclamic acid and sodium cyclamate with other cyclamates. Acta Crystallogr B. 2007 Jun;63(Pt 3):418-25. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.2546 mL | 26.2729 mL | 52.5458 mL | 131.3646 mL |
| 5 mM | 1.0509 mL | 5.2546 mL | 10.5092 mL | 26.2729 mL | |
| 10 mM | 0.5255 mL | 2.6273 mL | 5.2546 mL | 13.1365 mL | |
| 15 mM | 0.3503 mL | 1.7515 mL | 3.5031 mL | 8.7576 mL | |
| 20 mM | 0.2627 mL | 1.3136 mL | 2.6273 mL | 6.5682 mL | |
| 25 mM | 0.2102 mL | 1.0509 mL | 2.1018 mL | 5.2546 mL | |
| 30 mM | 0.1752 mL | 0.8758 mL | 1.7515 mL | 4.3788 mL | |
| 40 mM | 0.1314 mL | 0.6568 mL | 1.3136 mL | 3.2841 mL | |
| 50 mM | 0.1051 mL | 0.5255 mL | 1.0509 mL | 2.6273 mL | |
| 60 mM | 0.0876 mL | 0.4379 mL | 0.8758 mL | 2.1894 mL | |
| 80 mM | 0.0657 mL | 0.3284 mL | 0.6568 mL | 1.6421 mL | |
| 100 mM | 0.0525 mL | 0.2627 mL | 0.5255 mL | 1.3136 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.