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製品番号: HY-100404R

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DFMTI (Standard)

Name: DFMTI (Standard)
Brand: MedChemExpress
SKU: HY-100404R
Availability: PreOrder

(別名: MK5435 (Standard))

DFMTI (Standard) (MK5435 (Standard)) is the analytical standard of DFMTI (HY-100404). This product is intended for research and analytical applications. DFMTI is a blood-brain barrier-penetrant mGluR1 inhibitor. DFMTI abolishes the tobacco mosaic virus (TMV) resistance phenotype of NbAS-B-overexpressing plants by inhibiting glutamate production required for the activation of the Salicylic acid (HY-B0167) pathway. DFMTI disrupts prepulse inhibition in rats. DFMTI can be used in research related to psychiatric disorders and tobacco mosaic virus infection.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 864864-86-8
分子式: C₂₀H₁₈F₂N₄O
分子量:368.38

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

DFMTI (Standard) 構造式

CAS 番号: 864864-86-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information

説明

アプリケーション

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

化学情報

CAS 番号 864864-86-8
分子量 368.38
分子式 C₂₀H₁₈F₂N₄O
SMILES

O=C(N(C(C)C)C1)C2=C1C=C(C3=C(C)N(C4=CC=C(F)C=C4F)N=N3)C=C2
別名

MK5435 (Standard)
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

参考文献

[1]. Qiao G, et al. The Multifaceted Functions of Plant Asparagine Synthetase: Regulatory Mechanisms and Functional Diversity in Growth and Defense. Plants (Basel, Switzerland). 2026 Jan 24;15(3):362.

[2]. Hostetler ED, et al. Synthesis, characterization, and monkey PET studies of [¹⁸F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435. Synapse (New York, N.Y.). 2011 Feb;65(2):125-35. [Content Brief]

[3]. Cho HP, et al. A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptors. ACS chemical neuroscience. 2014 Jul 16;5(7):597-610. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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