Dimephosphon
Dimephosphon is an anti-inflammatory agent with antihistamine and antiserotonin activities. Dimephosphon helps maintain the conduction function of the spinal cord and reduces the excitability of spinal motor neurons in the area surrounding the lesion. Dimephosphon directly activates lymphatic vessel movement and improves lymphatic circulation. Dimephosphon can be used for the study of inflammatory edema, acute spinal cord injury and lymphatic circulation disorders.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 14394-26-4
- 分子式: C8H17O4P
- 分子量:208.19
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
Histamine Receptor アイソフォーム固有の製品をすべて表示
More
生物活性
Dimephosphon (2.5 % Dimephosphon Solution, 1 mL, daily for 10 days) promotes the recovery of spinal cord conduction function, and its mechanism may be related to anti-edema, vascular protection and reduction of neuronal hyperexcitability, in hybrid dogs with spinal cord injury[2].
Dimephosphon (50 mg/kg, i.p, once dose) enhances lymphatic circulation by directly activating lymphatic vessel contraction (stimulating vessel wall and valve muscle cells) in rats[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Albino rats (200-230 g)[3]
-
Dosage:50 mg/kg
-
Administration:Intraperitoneal injection (i.p.), once dose
-
Result:Increased the thoracic duct (TLD) lymph flow rate to 1.4 times that of the control group, and enhanced the contraction activity of lymphatic vessels. Increased the number of functional lymphatic vessels and the number of mesenteric lymphatic vessels by 1.5 times
化学情報
-
CAS 番号 14394-26-4
-
分子量 208.19
-
分子式 C8H17O4P
-
SMILES
O=C(CC(C)(P(OC)(OC)=O)C)C
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ziganshina LE, et al. [Effect of dimephosphon on the inflammatory reaction]. Farmakol Toksikol. 1988 May-Jun;51(3):58-60. [Content Brief]
[2]. A M Eremeev, et al. Effect of Dimephosphon on Functional Recovery of Damaged Spinal Cord. Bull Exp Biol Med. 2006 Feb;141(2):181-3. [Content Brief]
[3]. R Kh Khafiz'yanova, et al. Lymphotropic Effect of Dimephosphon, Mexidol, and Ketorolac is Realized via Activation of the Lymphangion and Stimulation of Lymph Formation. Bull Exp Biol Med. doi: 10.1007/s10517-007-0152-5. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Dimephosphon 関連分類
HY-176248 関連分類
Powered by Bioz