DK-139
DK-139 is a polyphenol compound bearing a cinnamaldehyde scaffol. DK-139 inhibits clonogenic growth of Cisplatin (HY-17394)-resistant human ovarian cancer. DK-139 can be used for the research of Cisplatin-resistant ovarian cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1426059-23-5
- 分子式: C18H18O5
- 分子量:314.33
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780cisR | GI50 |
11.3 μM
Compound: 17
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Growth inhibition of cisplatin-resistant human A2780cis cells after 7 days by crystal violet staining based clonogenic assay
Growth inhibition of cisplatin-resistant human A2780cis cells after 7 days by crystal violet staining based clonogenic assay
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[PMID: 24565968] |
DK-139 (Compound 17) (5-20 μM; 7 days) inhibits clonogenic growth of Cisplatin (HY-17394)-resistant human ovarian cancer A2780/Cis cells with a GI50 of 11.30 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Cisplatin-resistant human ovarian cancer A2780/Cis cells
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Concentration:5, 10, 20 μM
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Incubation Time:7 days
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Result:Exhibited a half-maximal cell growth inhibitory concentration (GI50) of 11.30 μM.
化学情報
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CAS 番号 1426059-23-5
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分子量 314.33
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分子式 C18H18O5
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SMILES
O=C(C1=CC(OC)=CC=C1O)/C=C/C2=CC(OC)=CC(OC)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)