DOPE-PEG2000-K237
DOPE-PEG2000-K237 (DOPE-PEG2000-Mal-Cys-HTMYYHHYQHHL) is an amphiphilic lipid-PEG-peptide conjugate composed of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the K237 peptide (sequence: HTMYYHHYQHHL). K237 peptide is a tumor-homing peptide identified by phage display that specifically binds to vasculature in tumor tissues. DOPE-PEG2000-K237 is used for tumor-targeted drug delivery via functionalization of liposomes and nanoparticles.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
DOPE-PEG2000-K237: surface modification of liposomes and lipid nanoparticles for tumor vasculature-targeted drug delivery and anti-angiogenic research.
Structural composition:
(1) DOPE; a phospholipid with two oleoyl chains that inserts into lipid bilayers as a hydrophobic anchor and provides fusogenic activity for endosomal escape;
(2) PEG2000; a hydrophilic polymer chain that forms a steric barrier reducing opsonization and RES clearance, thereby extending blood circulation time;
(3) K237 peptide; a tumor-homing peptide identified through phage display screening that specifically recognizes and binds to angiogenic tumor vasculature, directing nanocarriers to tumor blood vessels for enhanced drug deposition at tumor sites and anti-angiogenic effects.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
[DOPE-PEG2000-K237]
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別名
DOPE-PEG2000-Mal-Cys-HTMYYHHYQHHL
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)