DS08701581
DS08701581 is an inhibitor of FER tyrosine kinase with IC50. DS08701581 has anti-tumor activity and oral activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3074776-78-3
- 分子式: C26H32N8O2
- 分子量:488.58
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
EGFR アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | GI50 |
0.67 nM
Compound: 17c; DS08701581
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Inhibition of cell viability in mouse BaF3 cells expressing FER incubated for 3 days by Cell Titer Glo assay
Inhibition of cell viability in mouse BaF3 cells expressing FER incubated for 3 days by Cell Titer Glo assay
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[PMID: 39015278] |
| BaF3 | GI50 |
1000 nM
Compound: 17c; DS08701581
|
Inhibition of cell viability in mouse BaF3 cells incubated for 3 days by Cell Titer Glo assay
Inhibition of cell viability in mouse BaF3 cells incubated for 3 days by Cell Titer Glo assay
|
[PMID: 39015278] |
化学情報
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CAS 番号 3074776-78-3
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分子量 488.58
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分子式 C26H32N8O2
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SMILES
O=C1NN=CC2=C(C#N)C(N[C@H]3[C@@H](N)CCCC3)=NC(NC4=CC=CC(N5C[C@H](C)O[C@H](C)C5)=C4)=C21
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)