DYn-2
Based on 1 publication(s) in Google Scholar
DYn-2 (Anti-dynamin II) is a chemoselective sulfenylated protein probe. DYn-2 binds to sulfenylated proteins with chemoselectivity, enabling the detection of such proteins. DYn-2 can detect differences in intracellular sulfenylation rates. DYn-2 can be used in human cancer research, including studies on breast cancer and lung cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.77%
- CAS 番号: 1354630-46-8
- 分子式: C11H14O2
- 分子量:178.23
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 DYn-2
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生物活性
DYn-2 (1 mM; 15 min at 37 °C) selectively targets protein sulfenic acid modifications in recombinant yeast Gpx3, forming a single covalent adduct at the active site cysteine residue[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Recombinant Gpx3. 50 μM protein untreated or exposed to 100 μM.
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Concentration:1 mM.
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Incubation Time:For 15 min at 37 °C.
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Result:H2O2-dependent labeling of Gpx3 by DYn-2, with increased intensity relative to labeling by DAz-2.
化学情報
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CAS 番号 1354630-46-8
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性状 Solid
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分子量 178.23
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分子式 C11H14O2
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Color White to yellow
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SMILES
O=C1CCC(C(C1)=O)CCCC#C
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別名
Anti-dynamin II
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
溶剤 & 溶解度
DMSO : 100 mg/mL (561.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
純度とドキュメンテーション
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データシート (270 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Portuguese - PT (396 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6107 mL | 28.0536 mL | 56.1073 mL | 140.2682 mL |
| 5 mM | 1.1221 mL | 5.6107 mL | 11.2215 mL | 28.0536 mL | |
| 10 mM | 0.5611 mL | 2.8054 mL | 5.6107 mL | 14.0268 mL | |
| 15 mM | 0.3740 mL | 1.8702 mL | 3.7405 mL | 9.3512 mL | |
| 20 mM | 0.2805 mL | 1.4027 mL | 2.8054 mL | 7.0134 mL | |
| 25 mM | 0.2244 mL | 1.1221 mL | 2.2443 mL | 5.6107 mL | |
| 30 mM | 0.1870 mL | 0.9351 mL | 1.8702 mL | 4.6756 mL | |
| 40 mM | 0.1403 mL | 0.7013 mL | 1.4027 mL | 3.5067 mL | |
| 50 mM | 0.1122 mL | 0.5611 mL | 1.1221 mL | 2.8054 mL | |
| 60 mM | 0.0935 mL | 0.4676 mL | 0.9351 mL | 2.3378 mL | |
| 80 mM | 0.0701 mL | 0.3507 mL | 0.7013 mL | 1.7534 mL | |
| 100 mM | 0.0561 mL | 0.2805 mL | 0.5611 mL | 1.4027 mL |
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