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製品番号: HY-W053641

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(E)-2-Nitrocinnamic acid

Name: (E)-2-Nitrocinnamic acid
Brand: MedChemExpress
SKU: HY-W053641
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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(E)-2-Nitrocinnamic acid (Compound 1k) is an Acetylcholinesterase inhibitor. (E)-2-Nitrocinnamic acid is applicable to research related to Alzheimer's disease.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1013-96-3
分子式: C₉H₇NO₄
分子量:193.16

保管条件:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

(E)-2-Nitrocinnamic acid 構造式

CAS 番号: 1013-96-3

容量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

(E)-2-Nitrocinnamic acid (Compound 1k) is an Acetylcholinesterase inhibitor. (E)-2-Nitrocinnamic acid is applicable to research related to Alzheimer's disease^[1].

IC₅₀ & Target

^[1]

AChE

Cholinesterase (ChE) アイソフォーム固有の製品をすべて表示 :

AChE
BChE

体外実験

(E)-2-Nitrocinnamic acid (10 μM) exhibits weak inhibition of AChE (8.52% inhibition at 10 μM) and negligible inhibition of BChE (2.11% inhibition at 10 μM), with a calculated AChE binding energy of -6.33 kcal/mol^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

化学情報

CAS 番号 1013-96-3
性状 Solid
分子量 193.16
分子式 C₉H₇NO₄
SMILES

OC(/C=C/C1=C(C=CC=C1)[N+]([O-])=O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

プロトコル

All Animals and Diseases

Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Gießel JM, et al. Substituted cinnamic anhydrides act as selective inhibitors of acetylcholinesterase. Bioorg Chem. 2019;90:103058. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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