Erbicin
Erbicin is a single-chain antibody against the human ErbB2 receptor. Erbicin specifically binds to ErbB2-positive cells, inhibits receptor autophosphorylation, and is internalized by target cells. Erbicin can be used in breast cancer-related research.
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
Human
Erbicin (50-500 nM; 2 h) binds to soluble ErbB2-ECD with a Kd of 50 nM as measured by ELISA, and binds to ErbB2-positive cells with a Kd of 5 nM as measured by ELISA[1].
Erbicin (5-700 nM; 200 s association, 300 s dissociation) binds to soluble ErbB2-ECD, and its Kd is determined as 46.7 nM by SPR kinetic analysis[1].
Erbicin (~3 μM; 400 s intervals) binds to soluble ErbB2-ECD in solution, with a Kd of 77 nM and a binding stoichiometry of 1:1 measured by ITC[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
ERBB2/HER2/CD340
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
化学情報
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SMILES
[Erbicin]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Erbicin 関連分類
HY-P991979 関連分類
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