Esuprone
Based on 1 Customer Validation
Esuprone is a brain-penetrant, orally active and selective MAO A inhibitor with an IC50 of 7.3 nM. Esuprone can be used for neurological research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.67%
- CAS 番号: 91406-11-0
- 分子式: C13H14O5S
- 分子量:282.31
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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MAO-A 7.3 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 91406-11-0
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性状 Solid
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分子量 282.31
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分子式 C13H14O5S
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Color White to off-white
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SMILES
CC(C1=CC=C(OS(CC)(=O)=O)C=C1O2)=C(C)C2=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (177.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Löscher W, et al. Inhibition of monoamine oxidase type A, but not type B, is an effective means of inducing anticonvulsant activity in the kindling model of epilepsy. J Pharmacol Exp Ther. 1999 Mar;288(3):984-92. [Content Brief]
[2]. Bergström M, et al. MAO-A inhibition in brain after dosing with esuprone, moclobemide and placebo in healthy volunteers: in vivo studies with positron emission tomography. Eur J Clin Pharmacol. 1997;52(2):121-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5422 mL | 17.7110 mL | 35.4221 mL | 88.5551 mL |
| 5 mM | 0.7084 mL | 3.5422 mL | 7.0844 mL | 17.7110 mL | |
| 10 mM | 0.3542 mL | 1.7711 mL | 3.5422 mL | 8.8555 mL | |
| 15 mM | 0.2361 mL | 1.1807 mL | 2.3615 mL | 5.9037 mL | |
| 20 mM | 0.1771 mL | 0.8856 mL | 1.7711 mL | 4.4278 mL | |
| 25 mM | 0.1417 mL | 0.7084 mL | 1.4169 mL | 3.5422 mL | |
| 30 mM | 0.1181 mL | 0.5904 mL | 1.1807 mL | 2.9518 mL | |
| 40 mM | 0.0886 mL | 0.4428 mL | 0.8856 mL | 2.2139 mL | |
| 50 mM | 0.0708 mL | 0.3542 mL | 0.7084 mL | 1.7711 mL | |
| 60 mM | 0.0590 mL | 0.2952 mL | 0.5904 mL | 1.4759 mL | |
| 80 mM | 0.0443 mL | 0.2214 mL | 0.4428 mL | 1.1069 mL | |
| 100 mM | 0.0354 mL | 0.1771 mL | 0.3542 mL | 0.8856 mL |
Esuprone 関連分類
HY-106770 関連分類
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