ETZ
Based on 1 Customer Validation
ETZ (C3-CA-DTZ) is a promising luciferase substrate (prosubstrate) activatable in vivo by nonspecific esterase to enhance the brain delivery of the luciferin.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.84%
- CAS 番号: 2989379-61-3
- 分子式: C34H28N6O6
- 分子量:616.62
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
1. ETZ (6.8 mM) is made by dissolving 25% HP-β-CD and 20% PEG-400 in ~3 mL of normal saline pre-supplemented with 5% (w/v) NaHCO3.
2. 100 μL of ETZ (6.8 mM) is delivered to mice via tail vein right after intracranial cell injection.
3. Bioluminescence images are acquired with a BLI system.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2989379-61-3
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性状 Solid
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分子量 616.62
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分子式 C34H28N6O6
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Color Light yellow to orange
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SMILES
O=C(CCC(OCC1=CN(N=N1)CC(O)=O)=O)OC2=C(CC3=CC=CC=C3)N=C4C(C5=CC=CC=C5)=NC(C6=CC=CC=C6)=CN42
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別名
C3-CA-DTZ
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (162.17 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6217 mL | 8.1087 mL | 16.2174 mL | 40.5436 mL |
| 5 mM | 0.3243 mL | 1.6217 mL | 3.2435 mL | 8.1087 mL | |
| 10 mM | 0.1622 mL | 0.8109 mL | 1.6217 mL | 4.0544 mL | |
| 15 mM | 0.1081 mL | 0.5406 mL | 1.0812 mL | 2.7029 mL | |
| 20 mM | 0.0811 mL | 0.4054 mL | 0.8109 mL | 2.0272 mL | |
| 25 mM | 0.0649 mL | 0.3243 mL | 0.6487 mL | 1.6217 mL | |
| 30 mM | 0.0541 mL | 0.2703 mL | 0.5406 mL | 1.3515 mL | |
| 40 mM | 0.0405 mL | 0.2027 mL | 0.4054 mL | 1.0136 mL | |
| 50 mM | 0.0324 mL | 0.1622 mL | 0.3243 mL | 0.8109 mL | |
| 60 mM | 0.0270 mL | 0.1351 mL | 0.2703 mL | 0.6757 mL | |
| 80 mM | 0.0203 mL | 0.1014 mL | 0.2027 mL | 0.5068 mL | |
| 100 mM | 0.0162 mL | 0.0811 mL | 0.1622 mL | 0.4054 mL |